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Molecules on Second Life

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About Jean-Claude Bradley

Jean-Claude Bradley is an Associate Professor of Chemistry and the E-Learning Coordinator for the College of Arts and Sciences at Drexel University in Philadelphia, PA.

He teaches organic chemistry and runs UsefulChem, an open source science project dealing with the synthesis of anti-malarial compounds.

Chemistry Wide Open

Chemistry

Thanks to Joanna Scott, we've been taking advantage of our invitation to contribute to the Nature island on Second Life. Beth made a copy of the Open Notebook Science building and created a cemetery filled with blue obelisks so that multiple students can take organic chemistry quizzes at the same time. I'll be testing that shortly in my class to see how many students can comfortably compete in a virtual race.

Today I met Andrew Lang (Hiro Sheridan on SL) who has built a molecule rezzer on Nature Island. He has a nice little area where he displays some molecules (like cholesterol) and gives information about them on a screen. Andrew's rezzer takes hin (Hyperchem) files as input and I gave him one of ours to render after converting from sdf using OpenBabel.

I think that being able to walk around a molecule can add valuable new insight to thinking about and doing chemistry. It should also make it easier to explain some ideas. In about a month we'll be looking at chirality in my class and I can see how this could be really useful.

The molecule that I chose was predicted by Sean to dock into enoyl reductase (molecule 4 in D-EXP005). If possible it would be nice to show how it docks in Second Life. Andrew's rezzer is limited to about 80 atoms so we'll have to see if we can show enough of the docking site on the protein to see clearly.

Come on over to the Nature Island and let me know what you think! (slurl)

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Looks great!  So you are

Looks great!  So you are able to reformat from a file made outside second life to a file made inside second life?  Have you worked on trying to get different molecules to react together in second life?  I've though about somehow using the sensor function to sense different pKa values and then with a complicated mess of rez and die functions, you could generate the products from the different reactants. 

What really needs to happen

What really needs to happen is for someone to design a specific Virtual world environment for chemists.  Chemists need to design their own VW from scratch, that way we can customize all the functionality we need, then we could make it so our custom chem virtual world could be "mergable" with other virtual worlds like SL, so people can freely come and go as they please into different VWs.  This statement complies with the larger philosophy of standardizing the virtual world operational protocols so that people from different virtual world's can intermingle betwixt them without difficulty. 

Albert - yes the molecule is

Albert - yes the molecule is made from a HIN (hyperchem) file that can be converted easily from SDF using OpenBabel. I just copied it on a notecard and gave it to Hiro who used his rezzer to make the molecule in about a minute. I don't know if Hiro will make his rezzer available to anyone but you could ask him. He hangs around Nature Island these days.
I don't know about reactions in second life. Right now I just want to use it as a visualization, collaboration and teaching tool. But there are a lot more possibilities if someone were willing to take the time to implement ideas like that.

I just saw this MSNBC

I just saw this MSNBC article on chemistry and gaming: Battle aliens, save world, learn chemistry.

Yes, I've heard about this

Yes, I've heard about this game but I don't think it is openly available yet.

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