MIT engineers have created ultrathin films made of polymers that could be applied to medical devices and other surfaces to control microbe accumulation. The inexpensive, easy-to-produce films could provide a valuable layer of protection for the health care industry by helping to reduce the spread of hospital-acquired infections, which take the lives of 100,000 people and cost the United States an estimated $4.5 billion annually.
The researchers found they could control the extent of bacterial adhesion to surfaces by manipulating the mechanical stiffness of polymer films called polyelectrolyte multilayers. Thus, the films could be designed to prevent accumulation of hazardous bacteria or promote growth of desirable bacteria.
“All other factors being equal, mechanical stiffness of material surfaces increases bacterial adhesion,” said Krystyn Van Vliet, the Thomas Lord Assistant Professor of Materials Science and Engineering.











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